Published December 18, 1992
by Wiley-VCH .
Written in English
|The Physical Object|
|Number of Pages||380|
Oxford Chemistry Primers This book describes the coordination chemistry of macrocyclic ligands. It covers the common types and the main strategies for the synthesis of the free ligands and their metal complexes. It covers the thermodynamic and kinetic properties of . About this book The synthesis of macrocycles is an art in itself. Template-controlled synthesis provides elegant access to fascinating macrocyclic structures. This book contains an overview of complex formation by macrocyclic ligand systems. The study of macrocyclic chemistry represents a major area of activity which impinges on a range of other areas in both chemistry and biochemistry. The field has characteristically yielded many interesting and unusual by: host–guest chemistry of macrocyclic compounds are very useful in fundamental studies, e.g., in phase transfer c atalysis and biological studies.3 In situ, one pot template condensation reactions lie at the heart of macrocyclic chemistry.4 There-fore, template reactions have been widely used for the synthesis of macrocyclic.
Analytical Chemistry of Macrocyclic and Supramolecular Compounds [Khopkar, S.M.] on *FREE* shipping on qualifying offers. Analytical Chemistry of Macrocyclic and Supramolecular CompoundsCited by: Macrocyclic and Supramolecular Chemistry: How Izatt-Christensen Award Winners Shaped the Field features chapters written by the award recipients who provide unique perspectives on the spectacular growth in these expanding and vibrant fields of chemistry over the past half century, and on the role of these awardees in shaping this growth. During. The macrocyclic chemistry of Cram, Lehn, and Pedersen in the s fathered the supramolecular chemistry of today. The insights gained from their pioneering work with crown ethers, cryptands, and spherands have been valuable to many contemporary scientists. Phil Cox, PhD, Senior Principal Scientist, Chemistry Group Leader, Discovery Chemistry and Technology, AbbVie, Inc. This presentation will focus on the lessons learned from an initiative to analyze AbbVie’s internal database of compounds beyond Ro5 (including macrocycles). Rationalizing the Passive Membrane Permeability of Cyclic Peptides.
Coordination Chemistry of Macrocyclic Compounds (Oxford Chemistry Primers (72)) by Edwin C. Constable (Author) › Visit Amazon's Edwin C. Constable Page. Find all the books, read about the author, and more. See search results for this author. Are Cited by: Chelate and Macrocyclic Effects Last updated; Save as PDF Page ID ; No headers. Ligands that contain more than one binding site for a metal ion are called chelating ligands (from the Greek word χηλή, chēlē, meaning "claw"). As the name implies, chelating ligands have high affinity for metal ions relative to ligands with only one binding group (which are called monodentate. Macrocyclic compounds are known as a traditional supramolecule based on the specific channel where molecular recognition is possible. Up to the present, various crown ethers and calixarene derivatives including their inclusion phenomena have been reported. Here, a novel type of macrocyclic compounds based on benzoxazine dimers was proposed. 'This book that deals with a special class of host-guest chemistry, recognized by the Nobel Chemistry Prize Awards, should appeal to almost all chemists. Medicinal chemists, in particular, may find it a source of novel new approaches to potential therapeutic agents.' Journal of Medicinal Chemistry .